DEVELOPMENT OF TRIPTOLIDE SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM AND ITS ANTI-TUMOR EFFECT ON GASTRIC CANCER XENOGRAFTS

Development of Triptolide Self-Microemulsifying Drug Delivery System and Its Anti-tumor Effect on Gastric Cancer Xenografts

Purpose: To develop a triptolide (TP) self-microemulsifying drug delivery system and to investigate its anti-tumor effect on human gastric cancer line MGC80-3 xenografts in nude mice.Methods: The medium chain triglyceride (MCT) was selected as oil phase; polyoxyethylene castor oil (EL) was selected as surfactant, and PEG-400 was selected as cosurfa

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Formulation of Menthol-Loaded Nanostructured Lipid Carriers to Enhance Its Antimicrobial Activity for Food Preservation

Purpose: Due to the antimicrobial property, menthol have significant potential for food preservation and foodstuff shelf life improvement.Nevertheless, menthol instability, insolubility, and rapid crystallization in aqueous media make it unsuitable for used in food products.This work was aimed to prepare menthol-loaded nanostructured lipid carriers

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Effect of different types of fine aggregates on fatigue resistance and self-healing of fine aggregate asphalt matrices

corky lala Fatigue cracking is one of the most common types of distress in asphalt pavements.Each asphalt concrete (AC) constituent and its interactions are relevant to characterize the resistance to fatigue cracking of the ACs.Also, for the selection of materials, it is essential to consider not only the capacity of the material resist to fatigue

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Distribution of coat protein and nucleic acid of Plum pox virus (PPV) in seedlings of peach rootstock GF305 and apricot cv. Real Fino

In this work, the in-plant distribution of Plum pox virus (PPV) in seedlings of peach rootstock GF305 and apricot cv.Real Fino was studied.Symptom severity and the optical density with the ELISA-DASI test were il2510 determined in the leaves.Occurrence of the virus (coat protein and nucleic acid) in the stems and petioles was analyzed by tissue pri

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